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Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid iyo (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8

Sharaxaad Gaaban:

Qaanuunka molecular:C48H62N4O8
Miisaanka Molecular:823.028


Faahfaahinta Alaabta

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Sharaxaada

Dhexdhexaadiyaheena tofacitinib ayaa muhiim u ah habka wax soo saarka ee tofacitinib, daawo si fiican loo yaqaan oo loo isticmaalo daawaynta noocyada arthritis-ka qaarkood.Dhexdhexaadkani wuxuu door muhiim ah ka ciyaaraa wax soo saarka tofacitinib, isagoo gacan ka geysanaya waxtarkiisa iyo tayada.Via (2R,3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid iyo (3R,4R) -N,4-dimethyl-1- (phenylmethyl) - Isku-darka saxda ah ee 3-piperidinamines, our Alaabtu waxay hubisaa isku-dhafka tayada sare leh ee tofacitinib oo buuxiya oo ka sarreeya heerarka warshadaha.

Qaaciddada molecular iyo miisaanka dhexdhexaadkayaga tofacitinib waxay muujinaysaa nadiifnimadeeda iyo awooddeeda, taas oo ka dhigaysa qayb lagu kalsoonaan karo oo ka mid ah habka wax soo saarka daawada.Iyada oo si taxadar leh loo cabbiray maaddooyinka, dhexdhexaadkani wuxuu dammaanad qaadayaa joogteynta iyo waxtarka alaabta ugu dambeysa, tofacitinib.Hantideeda molecular waxay sidoo kale gacan ka geysataa xasilloonida guud ee tofacitinib iyo nolosha shelf, hubinta inay sii ahaato mid waxtar leh oo la isku halayn karo muddada fog.

Na Dooro

JDK waxay leedahay tas-hiilaadka wax soo saarka heerka koowaad iyo qalabka maaraynta tayada, kaas oo hubinaya sahayda xasilloon ee dhexdhexaadiyeyaasha API.Kooxda xirfadlayaasha ahi waxay xaqiijinayaan R&D alaabta.Labada dhinacba, waxaan ka raadineynaa CMO & CDMO suuqa gudaha iyo dibadda.


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